Targeted NGS amplicon Panels to fit your research and diagnostic needs
FOR EVERY APPLICATION: Tumor Profiling, Immuno-oncology, Cancer Liquid Biopsy, Inherited Diseases, Pharmacogenomics, Gene editing / CRISPR QC, Agrigenomics / Genotyping by Sequencing (GBS), Metagenomics.
CleanPlex® NGS panels are powered by Paragon Genomics’ CleanPlex Technology, which uses a proprietary multiplex PCR background cleaning chemistry to effectively remove non-specific PCR products, resulting in optimized, best-in-class target enrichment performance and efficient use of sequencing reads. → Save on sequencing costs
Low-input, fast 3h workflow and high performance NGS panels to target up to >20,000 amplicons in a single tube reaction. Available as catalog products and cost-efficient CUSTOM solutions. Especially suitable for clinical and translational research.
MULTIPLEX-PCR-BASED AMPLICON PANELS:
- Easy & fast (3h) single-tube workflow
- Input DNA as low as 0.1 – 10 ng
- Designed for germline & somatic variant detection, sensitivity down to 1% allele frequency (UMI –panels 0.1 %)
- Detection of and analysis for single nucleotide variants (SNVs), small insertions and deletions (Indels), copy number variations (CNVs), gene fusions / splice variants, gene expression level, tumor mutational burden (TMB), microsatellite instability (MSI), internal tandem duplication (ITD), etc.
- Sample Types: genomic DNA, FFPE, circulating cell-free DNA (cfDNA), fresh and frozen tissue
- Provides high on-target percentage and coverage uniformity >95%
- Compatible with Illumina, Ion Torrent and MGI platforms.
Available as CUSTOM – Ask for a free design quote to define Your Targets! Edit the catalog panels or design your own. Multiplex up to 20 000+ amplicons in each reaction. ALL-INCLUSIVE COST-EFFICIENT SOLUTION offering PCR primer pairs, lib prep reagents, unique dual indexed sequencing adapters and magnetic purification beads all in a single kit.
CATALOG PRODUCTS:
- CleanPlex® TMB 500 Panel
- CleanPlex® OncoZoom® Cancer Hotspot Panel
- CleanPlex® TP53 Panel
- CleanPlex® UMI Lung Cancer Panel
- OmniFusion™ RNA Lung Cancer Panel (To detect unknown fusions)
- AccuFusion™ RNA Lung Cancer Panel (To detect known fusions)
- CleanPlex® BRCA1 & BRCA2 Panel v3
- CleanPlex® Hereditary Cancer Panel v2 (to target 37 genes)
- CleanPlex® Mitochondrial Disease Panel
- CleanPlex® CFTR Panel
Swift Biosciences Accel-Amplicon NGS Panels
Prepare libraries in 2 Hours in a Single Tube
Swift Biosciences Accel-Amplicon NGS Panels utilize multiple tiled / overlapping amplicons to create a single tube, rapid 2-hour workflow to prepare ready-to-sequence libraries. This unique design enables applications utilizing limiting or damaged samples such as FFPE and cfDNA and provides powerful solutions for detecting variants and screening clinically relevant mutations with limit of detection down to 1%.
ONCOLOGY PANELS:
- Accel-Amplicon® Plus 57G Pan-Cancer Profiling Panel
- Accel-Amplicon® Plus Comprehensive TP53 Panel
- Accel-Amplicon® Plus Colorectal (CRC) Cancer Panel
- Accel-Amplicon® Plus EGFR Pathway Panel
- Accel-Amplicon® Plus Lung Cancer Panel
- Accel-Amplicon® Plus Myeloid Panel
GENETIC / INHERITED DISEASE PANELS:
- Accel-Amplicon® Plus BRCA1 And BRCA2 Panel
- Accel-Amplicon® Plus BRCA1, BRCA2, and PALB2 Panel
- Accel-Amplicon® Plus CFTR Panel
- Accel-Amplicon® Plus Lynch Syndrome Panel
For bacterial sequencing & microbiome /metagenomic analysis:
Swift Normalase® Amplicon 16S & ITS1 Panels (SNAP). Cover the whole region V1-V9 in a single multiplex-PCR-reaction – Detect more & new bacterial species from your samples!
Read more about Swift Biosciences CUSTOM panels here!
Check all our NGS solutions from here!
