Targeted NGS amplicon Panels to fit your research and diagnostic needs
FOR EVERY APPLICATION: Tumor Profiling, Immuno-oncology, Cancer Liquid Biopsy, Inherited Diseases, Pharmacogenomics, Gene editing / CRISPR QC, Agrigenomics / Genotyping by Sequencing (GBS), Metagenomics.
CleanPlex® NGS panels are powered by Paragon Genomics’ CleanPlex Technology, which uses a proprietary multiplex PCR background cleaning chemistry to effectively remove non-specific PCR products, resulting in optimized, best-in-class target enrichment performance and efficient use of sequencing reads. → Save on sequencing costs
Low-input, fast 3h workflow and high performance NGS panels to target up to >20,000 amplicons in a single tube reaction. Available as catalog products and cost-efficient CUSTOM solutions. Especially suitable for clinical and translational research.
MULTIPLEX-PCR-BASED AMPLICON PANELS:
- Easy & fast (3h) single-tube workflow
- Input DNA as low as 0.1 – 10 ng
- Designed for germline & somatic variant detection, sensitivity down to 1% allele frequency (UMI –panels 0.1 %)
- Detection of and analysis for single nucleotide variants (SNVs), small insertions and deletions (Indels), copy number variations (CNVs), gene fusions / splice variants, gene expression level, tumor mutational burden (TMB), microsatellite instability (MSI), internal tandem duplication (ITD), etc.
- Sample Types: genomic DNA, FFPE, circulating cell-free DNA (cfDNA), fresh and frozen tissue
- Provides high on-target percentage and coverage uniformity >95%
- Compatible with Illumina, Ion Torrent and MGI platforms.
Available as CUSTOM – Ask for a free design quote to define Your Targets! Edit the catalog panels or design your own. Multiplex up to 20 000+ amplicons in each reaction. ALL-INCLUSIVE COST-EFFICIENT SOLUTION offering PCR primer pairs, lib prep reagents, unique dual indexed sequencing adapters and magnetic purification beads all in a single kit.
- CleanPlex® TMB 500 Panel
- CleanPlex® OncoZoom® Cancer Hotspot Panel
- CleanPlex® TP53 Panel
- CleanPlex® UMI Lung Cancer Panel
- OmniFusion™ RNA Lung Cancer Panel (To detect unknown fusions)
- AccuFusion™ RNA Lung Cancer Panel (To detect known fusions)
- CleanPlex® BRCA1 & BRCA2 Panel v3
- CleanPlex® Hereditary Cancer Panel v2 (to target 37 genes)
- CleanPlex® Mitochondrial Disease Panel
- CleanPlex® CFTR Panel
Hybridization capture panels for targeted sequencing
myBaits target capture kits are compatible with any sequencing platform and with these in-solution biotinylated RNA probes you can target any region in a genome
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Design your own custom enrichment panels for your DNA/RNA/Methyl-Seq project with the assistance of Arbor’s team of expert scientists.