Oligos from Metabion
Top quality oligos, primers and probes for research and diagnostics from ISO-certified Metabion. Oligonucleotides for applications such as PCR, qPCR, NGS and RNA work. Do not hesitate to contact us, if you need customized oligo solutions. Register and order oligos here.
siRNA, shRNA, microRNA and lncRNA
Guaranteed gene silencing with Dharmacon/Horizon Discovery’s products
Predesigned and optimized products for gene regulation studies in mouse, rat and human. siRNAs available as single siRNAs, set of four siRNAs or SMARTpool – a mix of four siRNAs.
- ON-TARGETPlus siRNAs are designed for better specificity as their modifications dramatically reduce off-target effects.
- Accell siRNAs require no transfection reagent or viral delivery to difficult-to-transfect cell types such as neurons and primary cells.
- ON-TARGETPlus and Accel siRNAs are guaranteed to silence target gene expression by at least 75% at the mRNA level.
- Also positive and negative RNAi controls are available!
How to order? Search the right product(s) from Horizon Discovery’s web page by using Gene Id, ENTREZGENE or gene name and order by e-mail from: firstname.lastname@example.org.
CRISPR-Cas9 gene editing
Optimized tools for high-confidence genome engineering
The Dharmacon Edit-R CRISPR-Cas9 platform greatly simplifies the workflow of permanently knocking out genes. Their approach includes guaranteed, predesigned, ready-to-use guide RNAs and enables fast assessment of multiple target sites per gene for multiple genes.
CRISPR Guide RNA
High quality, ready-to-use lentiviral and synthetic reagents to guide Cas9 cleavage
Configure the optimal promoter for your cell type to ensure robust Cas9 expression or explore DNA-free options
CRISPR Controls and Detection Primers
Proper controls are essential to assessment of CRISPR-Cas9 genomic editing experiments
CRISPR-Cas9 Screening Libraries
Pooled sgRNA or arrayed crRNA for high-throughput gene editing studies
Check also QuickExtract™ DNA Extraction solution – easy DNA isolation for T7E1 CRISPR mutation detection.
Blog posts about CRISPR
Check the below blog pots written by our Product Manager Katja-Riikka Louhi, if interested in CRISPR applications:
BioVendor Offers Fast and Sensitive Solutions for miRNA Isolation and Quantification
miREIA Enzyme Immunoassay is a novel method for miRNA quantification applicable to studies on cancer, cardiovascular and pulmonary diseases as well as regulation of immunological processes.
qPCR KITS AND PANELS: MIRXES ID3EAL miRNA qPCR
miRNA qPCR high confidence and efficient Assays:
- 610 human microRNA Assays
- 241 mouse microRNA Assays
- 3,381 microRNA assays from other species
ID3EAL miRNA Knowledge Panels:
- Cancer miRNA Panel, 384 targets (352 miRNAs)
- Biofluid miRNA Panel, 192 targets (176 miRNAs)
Need to add colour to your nucleic acids?
Label IT – Mirus Bio solutions for labeling, modifying and tracking nucleic acids in vitro and in vivo
Label IT® Nucleic Acid Labeling Kits, read more
Efficient, direct, non-enzymatic labeling of DNA and RNA
Label IT® Nucleic Acid Modifying Kits, read more
Efficient, direct, non-enzymatic attachment of functional groups to DNA and RNA
Label IT® Tracker™ Intracellular Nucleic Acid Localization Kits, read more
Efficient, direct labeling of plasmid DNA for in vitro and in vivo tracking experiments
Label IT® siRNA Tracker™ Intracellular Localization Kit, read more
Efficient, direct labeling for in vitro and in vivo tracking of siRNA
Label IT® Plasmid Delivery Control, read more
Fluorescently labeled plasmid for in vitro and in vivo tracking
Label IT® RNAi Delivery Control, read more
Fluorescently labeled RNAi duplexes for in vitro or in vivo tracking